Investigation of EUD- and Dose-Volume Based NTCP Models for Rectal Bleeding, augmented by Principal Component Analysis of DVH Patterns

February 19, 2008

Oncozone Publications / Radiation Oncology / Online Article Locator

Title:     Investigation of EUD- and Dose-Volume Based NTCP Models for Rectal Bleeding, augmented by Principal Component Analysis of DVH Patterns
Authors:     M. Soehn*1, M. Alber*1, E. Meldolesi*2, C. Vargas*3, D. Yan*2. , 1University Hospital Tuebingen, Radiooncological Clinics, Sect. f. Biomedical Physics, Tuebingen, Germany, 2William Beaumont Hospital, Radiation Oncology, Royal Oak, MI, 3University of Florida, Radiation Oncology, Gainesville, FL, USA
Presenter:     Soehn Matthias

Keywords : analysis based bins bleeding c2 chronic complication component correlate cutoff cutoff-dose data dc dose dose-volume dvh et eud exp fig fit given grade ll logistic logit-eud lyman-eud measure model ntcp patients pca principal probability rectal regression resp resulting serial showed study summary tab technique toxicity used values variability wall

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Inverse Planning in Prostate Cancer

February 19, 2008

Oncozone Publications / Radiation Oncology / Online Article Locator

Title:     Inverse Planning in Prostate Cancer
Authors:     Vincent WC Wu1, Dora LW Kwong2, Jonathan ST Sham2 Hong Kong Polytechnic University1, University of Hong Kong2
Presenter:     Wu Vincent W.C.

Keywords : 3d 3dcrt al average bladder cancer compared comparison complicated conformal difference dose evaluate femoral for3d forward gy head however imrt intensity inv3d inverse methods ntcp oncol optimisation organ parameters patients plans probability prostate ptv radiotherapy reasonable received rectal rectum reduction require significant sparing target tcp tumour used views vol

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Intravesical markers for delineation of target volume during external focal irradiation of bladder carcinomas

February 19, 2008

Oncozone Publications / Radiation Oncology / Online Article Locator

Title:     Intravesical markers for delineation of target volume during external focal irradiation of bladder carcinomas
Authors:     MCCM Hulshof, G van Andel, JB van de Kamer, P Gangel, A Bel, Academical Medical Center, Amsterdam
Presenter:     Hulshof Maarten C.C.M.

Keywords : bladder clinical clips conclusions conebeam control ct-scan cystoscopic days delineation dept dose feasible fu future gy hyperthermia implantation increased insertion intravesical local markers months offers oncology overlapping painfull patients possibilities present procedure radiation rigid safe scan simple simulation stability study target toxicity treatment tumour used value verification visibility volume

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ntra-operative Prostate Brachytherapy – Can EUD assist D90 in assessing intra-operative implant dosimetry and quality

February 19, 2008

Oncozone Publications / Radiation Oncology / Online Article Locator

Title:     Intra-operative Prostate Brachytherapy – Can EUD assist D90 in assessing intra-operative implant dosimetry and quality
Authors:     S. Husain, P. Dunscombe, I. Kay, S. Angyalfi, D-A. Radford-Evans, G. Lim (Canada)
Presenter:     Husain Siraj

Keywords : alberta appears baker board brachytherapy calgary cancer centre changes clinical cold correlation d90 data different dose dr dvh emphasized equivalent et eud evaluating frcpc gy husain intra-operative inverse ldr md number oncologists parameter patients planning preferentially properties prostate r2 regions seed siraj spots system uniform university value varies volume

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Intra- and interfractional movements of the BeamCath urethral catheter for image-guided radiotherapy of prostate cancer

February 19, 2008

Oncozone Publications / Radiation Oncology / Online Article Locator

Title:     Intra- and interfractional movements of the BeamCath urethral catheter for image-guided radiotherapy of prostate cancer
Authors:     Henriette B. Honoré1, Per R. Poulsen1, and Morten Høyer2 Radiation treatment of prostate cancer is characterized by the necessity of a very high dose to the PTV region and a narrow margin to one of the risk organs, the rectum. A high geometrical precision is therefore needed. Both the prostate and the rectum have a large mobility. Daily patient positioning based on the location of the prostate itself can contribute to a significant margin reduction. Image guided prostate localization can be obtained by the BeamCath urethral catheter, which contains radiopaque fiducials for prostate visualization. In order to determine an appropriate CTV to PTV margin the position of the catheter relative to the bony anatomy and linac isocentre was investigated for repeated BeamCath sessions. Methods and Material Results Conclusions In the AP direction, which is most critical with regard to rectum sparing, the BeamCath technique allows a narrowing of the CTV to PTV margin. However, the technique seems to suffer from instabilities in the direction of the urethra. Further insight can be obtained from an analysis of the repeated CT scans where prostate and catheter movement can be separated (submitted for publication). 1 Department of Medical Physics and 2 Department of Oncology, Aarhus University Hospital, Denmark
Presenter:     Honoré Henriette B.

Keywords : anatomy ap balloon beamcath bladder bone cancer catheter caudal cc circles ct department direction displacement fiducial fields figure films four fractions green images inserted interfractional isocentre located margin mm movement narrow obtained patient planning portal position prostate ptv rectum red relative scan sessions setup symbols systematic technique treatment urethra

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Intensity-modulated radiotherapy (IMRT) as primary therapy for prostate cancer – experience of Ghent University Hospital (GUH)

February 19, 2008

Oncozone Publications / Radiation Oncology / Online Article Locator

Title:     Intensity-modulated radiotherapy (IMRT) as primary therapy for prostate cancer – experience of Ghent University Hospital (GUH)
Authors:     Gert De Meerleer (*), Valerie Fonteyne (*), Geert Villeirs (°), Luc Vakaet (*), Anthony Verbaeys (£), Ludwig Denoyette (*), Annick Van Greveling (*), Wilfried De Neve (*). Departments of Radiotherapy (*), Radiology (°) and Urology (£), Ghent University Hospital, Belgium (GUH)
Presenter:     De Meerleer Gert

Keywords : 74r72 76r74 abscise ad biochemical biol brfs cancer column curve dose figure follow-up fraction free gi gleason grade group gu guh gy imrt int intermediate median months ns oncol ordinate patients phys prostate psa r72 r74 radiat red relapse relative represents respectively risk score survival table therapy toxicity treated

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Influence Of Patient Selection On Outcome In Prostate Cancer Brachytherapy. The Experience Of The Paris Institut Curie/ Hopital Cochin / Hopital Necker Group On 809 Patients

February 19, 2008

Oncozone Publications / Radiation Oncology / Online Article Locator

Title:     Influence Of Patient Selection On Outcome In Prostate Cancer Brachytherapy. The Experience Of The Paris Institut Curie/ Hopital Cochin / Hopital Necker Group On 809 Patients
Authors:     L. Chauveinc*1, T. Flam*2, N. Thiounn*3, J. Rosenwald*1, S. Gomme*1, S. Solignac*1, D. Pontvert*1, B. Debre*2, J. Cosset*1. , 1Institut Curie, Paris, France, 2Hopital Cochin, Paris, France, 3H
Presenter:     Chauveinc Laurent

Keywords : 4-year abs brachytherapy cancer cochin coil complying criteria curie d90 date dfs difference disease-free either endorectal exactly france french frequent fulfilling gleason group hormone-therapy hospital implant institut lesser months necker normal outcome overall paris patients permanent pital prostate psa range results rmi score selection society survival thierry used v100

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IMRT, what have we learned? A systematic review in prostate cancer

February 19, 2008

Oncozone Publications / Radiation Oncology / Online Article Locator

Title:     IMRT, what have we learned? A systematic review in prostate cancer
Authors:     M. Mast, R. Wiggenraad, H. Struikmans Medical Centre The Hague
Presenter:     Mast Mirjam

Keywords : 3d-crt a2 acute al better cancer cm compared conclusions conventional ctv ctv-ptv decreased dose efficacy et evidence fu gi gr gu gy ii iii ijrobp imrt level median months nonrandomized optimal outcome phase prostate quality results rt rtog score seminal studies suggested survival td toxicity treatment trials vesicles vs zelefsky

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Improving the Therapeutic Ratio of Prostate Brachytherapy: Dose Escalation in I-125 Prostate Implants

February 19, 2008

Oncozone Publications / Radiation Oncology / Online Article Locator

Title:     Improving the Therapeutic Ratio of Prostate Brachytherapy: Dose Escalation in I-125 Prostate Implants
Authors:     J. Kao*, J. A. Cesaretti*, V. Dumane*, N. N. Stone*, R. G. Stock*. , Mount Sinai School of Medicine, New York, NY, USA
Presenter:     Kao Johnny

Keywords : af available bdfs biochemical biopsy bleeding brachytherapy cancer cc control d90 data dose dosimetry figure freedom grade gy i-125 implant intermediate ipss long-term median minimum monotherapy ollow-up oncology patients potent prior prof prostate psa range rectal results risk scores seed signif sinai t2c ter therapy unction urinary volume years

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Improving focal bladder treatment with IMRT

February 19, 2008

Oncozone Publications / Radiation Oncology / Online Article Locator

Title:     Improving focal bladder treatment with IMRT
Authors:     Dominique van Rooijen MSc*, Jeroen van de Kamer PhD, Maarten Hulshof PhD, Pieter Gangel, Arjan Bel PhD Dept. Radiation Oncology, Academic Medical Center, University of Amsterdam, The Netherlands
Presenter:     van Rooijen Dominique

Keywords : additional al analysis better bladder boost cancer conventional covered delineation differences dose elective et evaluated field fif figure four gtv gy imrt intestines lymph margin markers mm nodes normal oncol patients phd plans position prescribed ptv ptv40 ptvtumor receives rectum results risk sd technique tissue treatment tumor used volume

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